Tuberculosis TB today remains one of the world's most lethal infectious diseases. An estimated one-third of the world's population is infected with the tubercle bacillus-Mycobacterium tuberculosis Mtb , and 7 to 8 million people develop TB disease each year For purpose of clarity, TB infection latent TB is defined as harboring Mtb without evidence of active infection, and TB disease is active infection without Mtb based on clinical and laboratory findings. Recognizing that TB has been one of the most neglected international health problems and that the TB epidemic is rampant in many parts of the world, the World Health Organization WHO declared TB to be a global health emergency in The geriatric population among all ethnic groups and both genders, represent the largest reservoir of TB infection, particularly in developed nations 9.
Does tuberculosis threaten our ageing populations? | BMC Infectious Diseases | Full Text
US Pharm. Along with the elderly population's growth in numbers, there has been an increase in the number of tuberculosis TB cases among seniors. A form of disseminated TB, called miliary TB , is also relatively common in seniors. TB Infection Versus TB Disease TB infection is the term used to describe individuals who have contained the primary infection and who remain asymptomatic with a positive tuberculin skin test. Signs and Symptoms There is a major concern surrounding TB in seniors regarding failure to recognize or diagnose the disease. Since recommendations change due to resistant strains and newly developed information, consulting MMWR www.
Does tuberculosis threaten our ageing populations?
Tuberculosis in aging adults remains a clinical and epidemiological challenge. Atypical clinical manifestations of tuberculosis in older persons can result in delay in diagnosis and initiation of treatment; thus, unfortunately, higher rates of morbidity and mortality from this treatable infection can occur. Underlying illnesses, age-related diminution in immune function, the increased frequency of adverse drug reactions, and institutionalization can complicate the overall clinical approach to tuberculosis in elderly patients; maintenance of a high index of suspicion for tuberculosis in this vulnerable population is, thus, undoubtedly justifiable.
Metrics details. The purpose of this study was to evaluate the differences in clinical characteristics and treatment outcomes between older and younger tuberculosis TB patients in Korea. Dyspnea and comorbid medical conditions were more frequent and positive TB culture rates were higher in older TB patients. Incidence of adverse drug reactions did not differ between the two groups, except for severe gastrointestinal disorders. Treatment success and adverse drug reaction rates were similar in older and younger TB patients.